Real-World Evidence · AI · DataSUS

RWE Architect™From the research question to a submission-ready manuscript

A conversational platform that conducts real-world studies using Brazil's Unified Health System data — protocol, cohort, statistics, figures, and manuscript — with scientific rigor automatically verified at every stage.

4B+

outpatient care records

224M

hospital admission authorizations

246M

patients in the cross-database linkage catalog

STROBE + RECORD

reporting aligned with journal standards

The challenge

Brazil's public health data exists. The evidence rarely does.

Brazil's Unified Health System generates one of the world's largest health data collections. Turning it into publishable evidence still requires data engineering, biostatistics, and months of work — and an error in cohort definition becomes a plausible but incorrect number inside a paper.

Data that is difficult to access

Huge databases, different coding across systems, and patient linkage between databases.

Expensive, sequential teams

Data engineer, statistician, and writer working in sequence.

Silent errors

Ordinary AI writes convincing text even when the number is wrong.

How it works

From protocol to manuscript, with traceability

Seven connected stages, with every decision recorded and every result linked to its source.

01

Protocol first

Question, design, inclusion and exclusion criteria, index date, observation period, and statistical plan are recorded before any query, with the source of each decision — researcher, AI, or pending.

02

Database queries with transparent cost

Queries are generated and run automatically. Each is stored in full, with the volume read and cost.

03

Cohort validation

A step-by-step attrition table following STROBE, with every number produced by its source query. Patient counts are checked through two independent paths.

04

Statistical analysis

Kaplan-Meier, Cox, competing risks, propensity scores with covariate balance, and rates with confidence intervals.

05

Publication figures and tables

11 figure types at 300 DPI. Table 1 and the flowchart are assembled from computed data, never retyped.

06

Integrated literature

Searches in PubMed and ClinicalTrials.gov, with every cited reference supported by the recorded search.

07

Manuscript

AI drafts the sections. The researcher can edit any section on screen, and those edits are respected.

The databases

National data connected to the study question

Outpatient care (SIA)

More than 4 billion individualized procedures.

Specialized medicines

More than 420 million dispensations for treatment patterns and longitudinal follow-up.

Chemotherapy and radiotherapy

Approximately 62 million and 4 million records.

Hospital admissions (SIH)

224 million authorizations, with diagnoses, length of stay, ICU, and outcome.

Hospital Cancer Registries

The national INCA database, with 5.4 million cases, and the São Paulo Oncocentro Foundation database, with hormone receptors, HER2, recurrence, and vital status.

IBGE population

By municipality and year, for rates and incidence.

Your own data

Attach Excel or CSV files and integrate them into the study.

A catalog of 246 million patients makes it possible to follow the same patient across outpatient and hospital care. For cancer registries, the platform performs probabilistic linkage with chemotherapy and hospitalization data.

Core differentiator

Rigor verified, not promised

A plausible number, a polished figure, or a convincing sentence does not leave the platform if the method performed differs from the method declared.

The method described in the text is the method executed on the data — age range, period, and exclusion window.

Written hazard ratios, confidence intervals, medians, and p-values match the recorded analyses.

The strength of the conclusion matches the strength of the evidence: an observational study does not claim causality.

Every number in the selection flowchart comes from the query that produced it.

Rates have a declared and computed denominator.

Every cited figure and table exists, and every existing figure is cited.

Missing data is treated as missing, never as a clinical category.

Ethics, funding, and conflicts of interest are resolved.

The seal is granted, not requested

The “ready for publication” status is assigned by automatic evaluation, never by the AI, and is withdrawn if the study changes after approval.

Four dimensions, no average

Scientific integrity, reporting completeness (STROBE and RECORD), reproducibility, and submission completeness appear separately, because a completed checklist is not the same as correct science.

NewINAEP 2026 Guidance

AI and data governance

Governed AI, from the first turn to submission

Data classification

Each study states whether data is public and anonymized, pseudonymized, or identifiable; an ethical justification that contradicts that classification blocks the study.

AI model tracking

Every response records which model produced it. The model is selected and tested by Techtrials before use.

Protected identifiers

Columns that identify people, such as CPF and SUS Card, are withheld before reaching AI, including in client spreadsheets, and the researcher is warned before sending them.

Mandatory human review

No study reaches “ready for publication” without researcher confirmation. If the study changes, confirmation must be repeated.

AI use disclosure (ICMJE)

Generated from what actually happened. Sections written by the researcher are not attributed to AI, and human review is declared only when it occurred.

Analyses and figures

Robust methods, publication-ready outputs

Analyses

Kaplan-Meier with 95% CI and number at risk
Log-rank
Cox regression
Cumulative incidence with competing risks
Propensity score weighting and standardized-difference balance
Rates with Poisson confidence intervals
Monetary correction using a declared index
Automated Table 1

Figures

Survival curveForest plotAge pyramidMap by stateTime seriesBarsStacked barsBox plotScatter plotHeat mapSTROBE flowchart

300 DPI, opened full screen.

What you receive

A study prepared for review and submission

Manuscript in Word and PDF

A clean journal version and a blinded version without authors for peer review.

Submission package

Protocol, STROBE/RECORD checklist, declarations, supplementary material with the code list, attrition table, source data for every figure, and all executed queries.

Reproducibility stated honestly

Traceable, auditable, or computationally reproducible, according to what the study supports, with a guide for reproducing the analyses.

Governance record

AI and data governance record included in the package.

Who it is for

Evidence for those who research, decide, and transform care

Pharmaceutical industry

Medical Affairs, HEOR, and Market Access

Disease burden and epidemiology in Brazil's public health system, treatment patterns and therapy lines, resource use — admissions, length of stay, and ICU —, real-world survival, and local evidence for access and adoption discussions.

Researchers and academic institutions

National observational studies

Studies using national data without a data engineering team, with manuscripts structured from the outset for journal requirements.

Healthcare managers and medical societies

Care and population

Views of care by state and over time, with population rates.

The experience

Work in natural language

Study panel with protocol, evidence, and manuscript side by side

Your edits are respected by AI

Dark and light themes

Frequently asked questions

What researchers want to know

RWE Architect™

Real-world evidence from Brazil's public health system, at the speed of the question and with publication rigor.